Department of Pharmaceutical Chemistry

Current Research Projects

The Department of Pharmaceutical Chemistry has a broad range of research projects ranging from traditional pharmaceutics to biotechnology. Listed below are a several examples of the cutting edge research taking place within our program.

 

Current Research Projects
 
Monolithic Silica Columns for HILIC Analysis of Basic Drug Compounds Stobaugh Lab
Controlled release of immunomodulating peptides in Type-1 diabetes Topp Lab
Indentification of Binding Sites of ICAM-1 Peptides on the I-domain of LFA-1 Siahaan Lab
Treatment of metastatic breast cancer in the axilla nodes Forrest Lab
Protein structure in amorphous solids by hydrogen/deuterium exchange with MS analysis Topp Lab
Utilizing ICAM-1 Peptides to Target Drugs to Leukocytes using LFA-1 Receptor Siahaan Lab
Niemann-Pick C1 (NPC1): a Lysosomal Membrane Protein for Intracellular Drug Trafficking Krise Lab
Micro or Nano Particles For the Drug Development Process Berkland Lab
Binding and Internalization Properties of LFA-1-derived Peptides Siahaan Lab
Proteomic analysis of protein phosphorylation in aging cerebellum and skeletal muscle Schöneich Lab
Modulation of the Immunological Synapse by PLP-BPI for Suppressing EAE: A model for Multiple Sclerosis Siahaan Lab
Investigating the Prevalence of Intracellular Non-Productive Binding Events Krise Lab
Mechanisms of degradation of phenylephrine and cetirizine Topp Lab
Prodrug and nanocarrier design for treatment of melanoma Forrest Lab
Targeting the Immunological Synapse to Suppress of Type-1 Diabetes Siahaan Lab
Development of Fluorescent / Stable Isotope Tags for Proteins Containing DOPA Stobaugh Lab
Binding Mechanism of E-cadherin Peptides to Expressed E-cadherin: Modulators of Biological Barriers Siahaan Lab
Improving Physical Stability of EC1 Domain of E-cadherin by Blocking Its Free Thiol Siahaan Lab
Evaluating a New Approach to Enhance Selectivity of Drugs to Cancer Cells Krise Lab
Characterization of Lysosomotropic Drug Interactions Krise Lab
Intracellular Lipid Trafficking Disorders Resulting From Lysosomal Sequestration of Hydrophic Amines Krise Lab
Deamidation in the Fc portion of an IgG Topp Lab
Identification/Quantification of Post-translational Protein Modifications Schöneich Lab